Modified Growth Releasing Factor aminos 1-29, usually referred to as Modified GRF (1-29) or “ModGRF(1-29),” also known as CJC-1295 no DAC, is a synthetic analog of the endogenous peptide signaling potential hormone Growth Hormone Releasing Hormone (GHRH).
Endogenously produced GHRH has 44 amino acids in its chain structure. A truncated synthetic form of GHRH called Sermorelin or GRF 1-29 has 29 amino acids; Modified GRF (1-29) is further changed in that it has four substituted aminos in its chain that serve the purposes of potentially preventing degradation and oxidation in manufacture and transport as well as in vivo, while also increasing binding affinity to the GHRH receptors.
CJC-1295 and Ipamorelin (IPA) are commonly paired to support the body’s natural growth hormone release. This combination is often used to promote deeper sleep, improved recovery, enhanced lean muscle development, and better fat metabolism. Many users report improved training recovery, increased muscle fullness, and overall vitality, making it a popular stack for performance, body composition, and healthy aging support.
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