MGF 2 MG

MGF is 2 MG

Mechano Growth Factor (MGF), a member of the IGF-1 (insulin-like Growth Factor 1) super family, has been shown to be both exercise and age dependent.

MGF (also called IGF-1Ec), has a unique E domain with a 49bp insert in humans (52bp in rodents; IGF-1Eb), which results in a reading frame shift during the IGF-1 gene splicing to produce a distinct mature isoform.

Mechano growth factor (MGF) is a splice variant of IGF-1 first described in skeletal muscle. MGF may induce muscle cell proliferation in response to muscle stress and injury.

Endogenous expression of MGF was detected in neurogenic regions of the brain in control mice, and this expression declined with advancing age.